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Result: 1 - 4 of 4 rows are displayed

Molecule List for pathway CaM (Pathway Number 81) in Accession Synaptic_Network (Accession Number 16)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 CaMNetwork201000No
    There is a LOT of this in the cell: upto 1% of total protein mass. (Alberts et al, Mol Biol. of the Cell, Garland Publishers) Say 25 uM. Meyer et al Science 256 1199-1202 1992 refer to studies saying it is comparable to CaMK levels.
2 neurograninNetwork101000No
    Also known as RC3 and p17 and BICKS. Concentration in brain >> 2 uM from Martzen and Slemmon J Neurosci 64 92-100 1995. Concentration in dend spines is much higher than overall, so it could be anywhere from 2 uM to 50. We will estimate 10 uM as a starting point. Gerendasy et al JBC 269:35 22420-22426 1994 have a skeleton model (no numbers) indicating CaM-Ca(n) binding.
3 neurogranin*Network01000No
    The phosphorylated form of neurogranin does not bind CaM (Huang et al ABB 305:2 570-580 1993)
4 neurogranin-CaMNetwork01000No
    This is the CaM-bound form of neurogranin. This CaM is taken out of circulation and thus reduces the signaling through CaM.

 
Result: 1 - 4 of 4 rows are displayed



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