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Accession Type:
Network
Osc_Ca_
IP3metabolism
MIPP
CaMKII
CaM
PKC
IP3-3K
Gq
PLCbeta
134_dephos
145_dephos
IP4-system
IHP-system
1345_dephos
CaRegulation
Othmer-Tang-mode
l

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Accession information for Osc_Ca_IP3metabolism (Accession Number 24)

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Accession Basic Parameters

Name Osc_Ca_IP3metabolism
Accession Type Network
Transcriber Jyoti Mishra, NCBS
Developer Jyoti Mishra, NCBS
Entry Date (YYYY-MM-DD) 2002-01-08 00:00:00
Species Generic mammalian
Tissue Brain - Neuronal
Cell Compartment Cytosol
Source Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )
Methodology Quantitative match to experiments, Qualitative
Model Implementation Approximate implementation
Model Validation Approximates orginal data
Notes This network models an oscillatory calcium response to GPCR mediated PLCbeta activation, alongwith detailed InsP3 metabolism in the neuron. It differs from the NonOsc_Ca_IP3metabolism network in the CaRegulation module and in InsP3 receptor kinetics. Details of InsP3 receptor kinetics have been adapted from the Othmer-Tang model for oscillatory Ca dynamics. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc24.g   
GENESIS Format (Annotated version)    Anno_acc24.g   



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