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Accession information for RasGTPase (Accession Number 71)

Reaction Scheme

Accession Basic Parameters

Name RasGTPase
Accession Type Pathway
Transcriber Sharat J. Vayttaden and Pragati Jain, NCBS
Developer Robert A. Phillips, Jackie L. Hunter, John F. Eccleston, and Martin R. Webb
Entry Date (YYYY-MM-DD) 2006-05-12 00:00:00
Species General Mammalian
Tissue E.coli Expression system
Cell Compartment Cytosol
Source Phillips RA et al Biochemistry. 2003 Apr 8;42(13):3956-65. ( Peer-reviewed publication )
Methodology Qualitative
Model Implementation Exact GENESIS implementation
Model Validation Approximates original data
Notes Ras is an important regulator of cell growth in all eukaryotic cells. The model represent hydrolysis of active Ras-bound GTP to give inactive Ras-bound GDP catalyzed by GTPase activating proteins i.e NF1. The inactive Ras-bound GDP turns signalling protein off.

Conversion formats

Native Format (GENESIS format)    acc71.g   
MATLAB format    acc71.m   
SBML format    acc71.xml   

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