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Accession Type:
Network
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
PKC
MAPK
Ras
CaM
PKM
chain
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
PKC
MAPK
Ras
CaM
PKM
kinetics[1]
PKC
MAPK
Ras
CaM
PKM
kinetics[2]
PKC
MAPK
Ras
CaM
PKM
kinetics[3]
PKC
MAPK
MAPK
Ras
CaM
PKM
kinetics[4]
PKC
MAPK
Ras
CaM
PKM
kinetics[5]
PKC
MAPK
Ras
kinetics[6]
CaM
PKM
PKC
MAPK
Ras
CaM
PKM
kinetics[7]
PKC
Ras
CaM
PKM
kinetics[8]
PKC
MAPK
Ras
CaM
PKM
kinetics[9]
PKC
MAPK
Ras
CaM
PKM
kinetics[10]
PKC
MAPK
Ras
CaM
PKM
kinetics[11]
PKC
MAPK
Ras
CaM
PKM
kinetics[12]
PKC
MAPK
Ras
CaM
PKM
kinetics[13]
PKC
MAPK
Ras
CaM
PKM
kinetics[14]
PKC
MAPK
Ras
CaM
PKM
kinetics[15]
PKC
MAPK
Ras
CaM
PKM
kinetics[16]
PKC
MAPK
Ras
CaM
PKM
kinetics[17]
PKC
MAPK
Ras
CaM
PKM
kinetics[18]
PKC
MAPK
Ras
CaM
PKM
kinetics[19]
PKC
MAPK
Ras
CaM
PKM
kinetics[20]
PKC
MAPK
Ras
CaM
PKM
kinetics[21]
PKC
MAPK
Ras
CaM
PKM
kinetics[22]
PKC
MAPK
Ras
CaM
PKM
kinetics[23]
PKC
MAPK
Ras
CaM
PKM

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Accession information for Ajay_bhalla_2007_ReacDiff1_1e-12 (Accession Number 81)

Reaction Scheme

Accession Basic Parameters

Name Ajay_bhalla_2007_ReacDiff1_1e-12
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2006-12-08
Species Rat
Tissue Hippocampal CA1
Cell Compartment Dendrite
Source Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87
Methodology Semi-Quantitative match to experiments
Model Implementation Exact GENESIS implementation
Model Validation Replicates original data A, Replicates original data
Notes This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper

Conversion formats

FormatFile
Native Format (GENESIS format)    acc81.g   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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