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Accession Type:
Network
Ajay_bhalla_
2007_ReacDiff1_
1e-12
Shared_Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
PKC
MAPK
Ras
CaM
PKM
chain
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[1]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[2]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[3]
PKC
MAPK
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[4]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[5]
PKC
MAPK
Ras
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[6]
CaM
PKM
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[7]
PKC
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[8]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[9]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[10]
PKC
MAPK
 Molecule
 Enzyme
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[11]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[12]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[13]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[14]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[15]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[16]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[17]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[18]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[19]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[20]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[21]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[22]
PKC
MAPK
Ras
CaM
PKM
Shared Object_
Ajay_bhalla_
2007_ReacDiff1_
1e-12_[23]
PKC
MAPK
Ras
CaM
PKM

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Parameters for MAPK (Pathway Number 444)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 444
Accession Number 81
Accession Name Ajay_bhalla_2007_ReacDiff1_1e-12
Species Rat
Tissue Hippocampal CA1
CellCompartmentDendrite
Related Pathways 6, 24, 35, 56, 61, 75, 139, 142, 182, 193, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066, 1103
Notes  This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-12_Fig4A which was used for the model to replicate Figure 4A from the paper.
This stimulus file pkm_mapk22_diff_1e-12_Fig4G which was used for the model to replicate Figure 4G from the paper

Statistics

Reactions
10
6
0

Conversion format

This pathway is part of accession 81 and is completely specified in the file acc81.g.
There is no separate file for just this pathway.
FormatFile
Native Format (GENESIS format)    acc81.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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