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Accession Type:
Network
fig2_egfr
Shared_Object_
fig2_egfr
PKC
PLA2
PLCbeta
Gq
MAPK
 Molecule
 Enzyme
Ras
EGFR
Sos
PLC_g
CaRegulation

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Parameters for MAPK (Pathway Number 6)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 6
Accession Number 1
Accession Name fig2_egfr
Species Generic mammalian
Tissue Brain
CellCompartmentSurface - Nucleus
Related Pathways 24, 35, 56, 61, 75, 139, 142, 182, 193, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 444, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066, 1103
Notes This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse.
Demonstration script files for generating the figures in the paper, including figure 2, are available here.

Statistics

Reactions
9
4
0

Conversion format

This pathway is part of accession 1 and is completely specified in the file acc1.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc1.g   
GENESIS Format (Annotated version)    Anno_acc1.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.