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Accession Type:
Network
Synaptic_
Network
Shared_Object_
Synaptic_
Network
PKC
PLA2
PLCbeta
Gq
MAPK
 Molecule
 Enzyme
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
PP2B
PKA
AC
CaRegulation

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Parameters for MAPK (Pathway Number 75)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 75
Accession Number 16
Accession Name Synaptic_Network
Species Generic mammalian
Tissue Neuronal
CellCompartmentSynapse
Related Pathways 6, 24, 35, 56, 61, 139, 142, 182, 193, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 444, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066, 1103
Notes The Mitogen Activated Protein Kinase (MAPK) cascade model here includes both the MAPK cascade and its regulation by MKP-1. MKP-1 is induced upon MAPK activation, whereas MKP-2 is treated as a steady level of protein. For the purposes of this version of the model, MKP-1 is kept at a fixed starting value. The phosphatase Protein phosphatase 2 A (PP2A) is also included in this model to balance the activity of the kinases.

Statistics

Reactions
9
4
0

Conversion format

This pathway is part of accession 16 and is completely specified in the file acc16.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc16.g   
GENESIS Format (Annotated version)    Anno_acc16.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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