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Parameters for MAPK (Pathway Number 193) Pathway Layout
Pathway Basic Parameters | Pathway Name | MAPK | | Pathway Entry Number | 193 | | Accession Number | 45 | | Accession Name | MAPK_Asthagiri_adapt_fb | | Species | Chinese hamster (Cricetulus griseus); mammalian | | Tissue | Ovary - CHO cell line | | CellCompartment | Surface, cytosol | | Related Pathways | 6,
24,
35,
56,
61,
75,
139,
142,
182,
211,
230,
317,
335,
352,
366,
371,
377,
384,
390,
396,
402,
403,
409,
415,
421,
432,
438,
444,
450,
456,
462,
468,
474,
480,
486,
492,
498,
504,
510,
516,
522,
528,
535,
541,
547,
553,
559,
565,
571,
577,
583,
589,
595,
601,
607,
613,
619,
625,
631,
637,
643,
649,
655,
661,
667,
673,
679,
686,
692,
699,
704,
710,
716,
722,
728,
734,
740,
746,
752,
758,
764,
770,
776,
782,
788,
794,
800,
806,
812,
818,
824,
830,
836,
842,
848,
854,
860,
866,
872,
878,
884,
890,
896,
902,
908,
914,
921,
928,
934,
940,
946,
952,
958,
960,
965,
971,
977,
983,
989,
995,
1006,
1012,
1018,
1024,
1030,
1036,
1042,
1048,
1054,
1060,
1066
| | Notes | This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines, particularly the role of adapter targeted negative feedback mechanism in generating complete signal adaptation. This model simulates the results as per the figure 7A of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39.
| Statistics Conversion formatThis pathway is part of accession 45 and is completely specified in the file acc45.g.
There is no separate files for just this pathway. |
Pathway Detail Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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