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Accession Type:
Network
mkp1_feedback_
effects
Shared_Object_
mkp1_feedback_
effects
Sos
PKC
MAPK
 Molecule
 Enzyme
 Reaction
PLA2
Ras
PDGFR

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Parameters for MAPK (Pathway Number 35)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 35
Accession Number 4
Accession Name mkp1_feedback_effects
Species Generic mammalian
Tissue NIH 3T3 Expression
CellCompartmentSurface - nucleus
Related Pathways 6, 24, 56, 61, 75, 139, 142, 182, 193, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 444, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066, 1103
Notes The Mitogen Activated Protein Kinase (MAPK) cascade model here includes both the MAPK cascade and its regulation by two forms of MKP. MKP-1 is induced upon MAPK activation, whereas MKP-2 is treated as a steady level of protein. The phosphatase Protein phosphatase 2 A (PP2A) is also included in this model to balance the activity of the kinases.

Statistics

16
9
8

Conversion format

This pathway is part of accession 4 and is completely specified in the file acc4.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc4.g   
GENESIS Format (Annotated version)    Anno_acc4.g   
MATLAB format    acc4.m   
SBML format    acc4.xml   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.