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Accession Type:
Network
fig2_egfr
Shared_Object_
fig2_egfr
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaRegulation

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Accession information for fig2_egfr (Accession Number 1)

Reaction Scheme

Accession Basic Parameters

Name fig2_egfr
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2001-11-07
Species Generic mammalian
Tissue Brain
Cell Compartment Surface - Nucleus
Source Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )
Methodology Quantitative match to experiments, Hypothetical
Model Implementation Exact GENESIS implementation
Model Validation Approximates orginal data, Quantitatively predicts new data
Notes This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse.
Demonstration script files for generating the figures in the paper, including figure 2, are available here.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc1.g   
GENESIS Format (Annotated version)    Anno_acc1.g   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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