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Molecule Parameter List for CaN-CaM

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaN-CaM participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII33Network
Shared_Object_CaMKII CaM CaMKII 
CaN 
This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.

CaN-CaM acting as a Molecule in  
CaMKII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaN-CaMCaMKII
Accession No. : 33
CaN
Pathway No. : 175
00.1309No

CaN-CaM acting as a Substrate in a reaction in  
CaMKII Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
CaN-CaM-bind-CaCaMKII
Accession No. : 33
CaN
Pathway No. : 175
100.004
(uM^-1 s^-1)
60
(s^-1)
Kd(bf) = 0.6(uM)-Substrate
Ca
CaN-CaM

Product
CaN-CaMCa

CaN-CaM acting as a Product in a reaction in  
CaMKII Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
CaN-bind-CaMCaMKII
Accession No. : 33
CaN
Pathway No. : 175
0.2
(uM^-1 s^-1)
5000
(s^-1)
Kd(bf) = 25000(uM)-Substrate
CaM
CaN

Product
CaN-CaM



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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