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Molecule Parameter List for CaN-CaMCa4

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaN-CaMCa4 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000002

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII33Network
Shared_Object_CaMKII CaM CaMKII 
CaN 
This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.

CaN-CaMCa4 acting as a Molecule in  
CaMKII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaN-CaMCa4CaMKII
Accession No. : 33
CaN
Pathway No. : 175
00.1309No

CaN-CaMCa4 acting as a Product in a reaction in  
CaMKII Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
 NameAccession NamePathway NameKfKbKdtauReagents
1CaN-bind-CaMCa4CaMKII
Accession No. : 33
CaN
Pathway No. : 175
100.004
(uM^-1 s^-1)
0.6
(s^-1)
Kd(bf) = 0.006(uM)-Substrate
CaMCa4
CaN

Product
CaN-CaMCa4
2
  • CaN-CaMCa3-bind-
    Ca
  • CaMKII
    Accession No. : 33
    CaN
    Pathway No. : 175
    100.004
    (uM^-1 s^-1)
    30
    (s^-1)
    Kd(bf) = 0.3(uM)-Substrate
    Ca
    CaN-CaMCa3

    Product
    CaN-CaMCa4



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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