NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for Raf-GTP-Ras

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Raf-GTP-Ras participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences40080003979

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff2
  • 83NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff PKC MAPK 
    Ras CaM PKM chain kinetics PKC MAPK Ras CaM PKM kinetics[1] 
    PKC MAPK Ras kinetics[3] CaM PKM kinetics[2] PKC MAPK Ras 
    CaM PKM PKC MAPK Ras CaM PKM kinetics[4] PKC MAPK Ras CaM 
    PKM kinetics[5] PKC MAPK Ras CaM PKM kinetics[6] PKC MAPK 
    Ras CaM PKM kinetics[7] PKC MAPK Ras CaM PKM kinetics[8] 
    PKC MAPK Ras CaM PKM kinetics[9] PKC MAPK Ras CaM PKM kinetics[10] 
    PKC MAPK Ras CaM PKM kinetics[11] PKC MAPK Ras CaM PKM kinetics[12] 
    PKC MAPK Ras CaM PKM kinetics[13] PKC MAPK Ras CaM PKM kinetics[14] 
    PKC MAPK Ras CaM PKM kinetics[15] PKC MAPK Ras CaM PKM kinetics[16] 
    PKC MAPK Ras CaM PKM kinetics[17] PKC MAPK Ras CaM PKM kinetics[18] 
    PKC MAPK Ras CaM PKM kinetics[19] PKC MAPK Ras CaM PKM kinetics[20] 
    PKC MAPK Ras CaM PKM kinetics[21] PKC MAPK Ras CaM PKM kinetics[22] 
    PKC MAPK Ras CaM PKM kinetics[23] PKC MAPK Ras CaM PKM kinetics[24] 
    PKC MAPK Ras CaM PKM kinetics[25] PKC MAPK Ras CaM PKM kinetics[26] 
    PKC MAPK Ras CaM PKM kinetics[27] PKC MAPK Ras CaM PKM kinetics[28] 
    PKC MAPK Ras CaM PKM kinetics[29] PKC MAPK Ras CaM PKM kinetics[30] 
    PKC MAPK Ras CaM PKM kinetics[31] PKC MAPK Ras CaM PKM kinetics[32] 
    PKC MAPK Ras CaM PKM kinetics[33] PKC MAPK Ras CaM PKM kinetics[34] 
    PKC MAPK Ras CaM PKM kinetics[35] PKC MAPK Ras CaM PKM kinetics[36] 
    PKC MAPK Ras CaM PKM kinetics[37] PKC MAPK Ras CaM PKM kinetics[38] 
    PKC MAPK Ras CaM PKM 
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
    The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.

    Raf-GTP-Ras acting as a Molecule in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 686
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 692
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 699
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 704
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 710
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 716
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 722
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 728
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 734
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 740
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 746
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 752
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 758
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 764
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 770
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 776
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 782
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 788
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 794
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 800
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 806
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 812
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 818
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 824
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 830
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 836
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 842
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 848
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 854
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 860
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 866
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 872
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 878
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 884
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 890
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 896
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 902
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 908
    01.5No
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 679
    01.5Yes
    Raf-GTP-Ras
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 914
    01.5Yes

    Raf-GTP-Ras acting as an Enzyme in  
    Ajay_Bhalla_2007_ReacDiff2 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 679
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    2Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 679
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    3Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 686
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    4Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 686
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    5Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 692
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    6Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 692
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    7Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 699
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    8Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 699
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    9Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 704
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    10Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 704
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    11Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 710
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    12Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 710
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    13Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 716
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    14Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 716
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    15Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 722
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    16Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 722
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    17Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 728
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    18Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 728
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    19Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 734
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    20Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 734
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    21Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 740
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    22Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 740
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    23Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 746
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    24Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 746
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    25Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 752
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    26Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 752
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    27Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 758
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    28Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 758
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    29Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 764
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    30Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 764
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    31Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 770
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    32Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 770
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    33Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 776
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    34Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 776
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    35Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 782
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    36Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 782
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    37Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 788
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    38Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 788
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    39Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 794
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    40Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 794
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    41Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 800
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    42Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 800
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    43Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 806
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    44Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 806
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    45Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 812
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    46Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 812
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    47Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 818
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    48Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 818
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    49Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 824
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    50Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 824
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    51Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 830
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    52Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 830
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    53Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 836
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    54Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 836
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    55Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 842
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    56Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 842
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    57Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 848
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    58Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 848
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    59Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 854
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    60Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 854
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    61Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 860
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    62Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 860
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    63Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 866
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    64Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 866
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    65Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 872
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    66Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 872
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    67Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 878
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    68Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 878
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    69Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 884
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    70Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 884
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    71Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 890
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    72Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 890
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    73Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 896
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    74Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 896
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    75Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 902
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    76Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 902
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    77Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 908
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    78Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 908
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    79Raf-GTP-Ras /
    Raf-GTP-Ras.1
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 914
    0.1590960.34explicit E-S complexSubstrate
    MAPKK

    Product
    MAPKK-ser
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).
    80Raf-GTP-Ras /
    Raf-GTP-Ras.2
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • MAPK
    Pathway No. : 914
    0.1590960.34explicit E-S complexSubstrate
    MAPKK-ser

    Product
    MAPKK*
        Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591).

    Raf-GTP-Ras acting as a Substrate in a reaction in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    2diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    3diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    5diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    6diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    8diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    9diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    10diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    12diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    14diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    15diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    17diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    18diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    20diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    21diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    23diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    24diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    26diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    27diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    29diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    30diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    32diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    33diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    35diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    36diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    38diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    39diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras

    Raf-GTP-Ras acting as a Product in a reaction in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    2
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    3diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    4
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics
    Pathway No. : 684
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    5diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    6
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[1]
    Pathway No. : 690
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    8
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[2]
    Pathway No. : 697
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    9diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    10
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[3]
    Pathway No. : 694
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    12
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[4]
    Pathway No. : 708
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    14
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[5]
    Pathway No. : 714
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    15diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    16
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[6]
    Pathway No. : 720
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    17diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    18
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[7]
    Pathway No. : 726
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    20
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[8]
    Pathway No. : 732
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    21diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    22
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[9]
    Pathway No. : 738
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    23diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    24
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[10]
    Pathway No. : 744
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    26
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[11]
    Pathway No. : 750
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    27diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    28
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[12]
    Pathway No. : 756
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    29diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    30
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[13]
    Pathway No. : 762
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    32
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[14]
    Pathway No. : 768
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    33diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    34
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[15]
    Pathway No. : 774
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    35diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    36
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[16]
    Pathway No. : 780
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    38
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[17]
    Pathway No. : 786
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    39diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    40
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[18]
    Pathway No. : 792
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    41diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    42
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[19]
    Pathway No. : 798
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    44
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[20]
    Pathway No. : 804
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    45diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    46
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[21]
    Pathway No. : 810
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    47diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    48
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[22]
    Pathway No. : 816
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    49diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    50
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[23]
    Pathway No. : 822
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    51diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    52
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[24]
    Pathway No. : 828
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    53diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    54
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[25]
    Pathway No. : 834
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    55diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    56
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[26]
    Pathway No. : 840
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    57diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    58
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[27]
    Pathway No. : 846
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    59diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    60
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[28]
    Pathway No. : 852
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    61diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    62
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[29]
    Pathway No. : 858
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    63diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    64
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[30]
    Pathway No. : 864
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    65diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    66
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[31]
    Pathway No. : 870
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    67diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    68
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[32]
    Pathway No. : 876
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    69diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    70
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[33]
    Pathway No. : 882
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    71diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    72
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[34]
    Pathway No. : 888
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    73diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    74
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[35]
    Pathway No. : 894
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    75diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    76
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[36]
    Pathway No. : 900
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    77diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    Raf-GTP-Ras

    Product
    Raf-GTP-Ras
    78
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[37]
    Pathway No. : 906
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.
    79
  • Ras-act-unphosph
    -raf
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • kinetics[38]
    Pathway No. : 912
    0
    (uM^-1 s^-1)
    0
    (s^-1)
    --Substrate
    GTP-Ras
    craf-1

    Product
    Raf-GTP-Ras
      18 May 2003. This reaction is here to provide basal activity for MAPK as well as the potential for direct EGF stimulus without PKC activation. Based on model from FB/fb28c.g: the model used for MKP-1 turnover. The rates there were constrained by basal activity values.



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.