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Molecule Parameter List for CaM-Ca4

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*CaM-Ca4* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	40	0	0	0	0	119	79

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff2	83	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, kinetics[3], CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, CaM, PKM, kinetics[6], PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM, kinetics[24], PKC, MAPK, Ras, CaM, PKM, kinetics[25], PKC, MAPK, Ras, CaM, PKM, kinetics[26], PKC, MAPK, Ras, CaM, PKM, kinetics[27], PKC, MAPK, Ras, CaM, PKM, kinetics[28], PKC, MAPK, Ras, CaM, PKM, kinetics[29], PKC, MAPK, Ras, CaM, PKM, kinetics[30], PKC, MAPK, Ras, CaM, PKM, kinetics[31], PKC, MAPK, Ras, CaM, PKM, kinetics[32], PKC, MAPK, Ras, CaM, PKM, kinetics[33], PKC, MAPK, Ras, CaM, PKM, kinetics[34], PKC, MAPK, Ras, CaM, PKM, kinetics[35], PKC, MAPK, Ras, CaM, PKM, kinetics[36], PKC, MAPK, Ras, CaM, PKM, kinetics[37], PKC, MAPK, Ras, CaM, PKM, kinetics[38], PKC, MAPK, Ras, CaM, PKM
This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one. The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.

CaM-Ca4 acting as a Molecule in Ajay_Bhalla_2007_ReacDiff2 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 688	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 695	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 701	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 706	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 712	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 718	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 724	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 730	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 736	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 742	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 748	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 754	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 760	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 766	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 772	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 778	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 784	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 790	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 796	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 802	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 808	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 814	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 820	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 826	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 832	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 838	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 844	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 850	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 856	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 862	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 868	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 874	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 880	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 886	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 892	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 898	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 904	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 910	0	1.5	No
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 681	0	1.5	Yes
CaM-Ca4	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 916	0	1.5	Yes

CaM-Ca4 acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 680	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
2	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
3	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 682	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
4	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 687	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
5	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
6	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 689	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
7	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 693	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
8	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
9	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 696	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
10	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 700	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
11	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
12	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 702	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
13	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 705	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
14	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
15	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 707	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
16	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 711	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
17	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
18	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 713	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
19	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 717	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
20	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
21	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 719	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
22	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 723	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
23	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
24	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 725	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
25	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 729	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
26	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
27	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 731	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
28	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 735	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
29	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
30	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 737	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
31	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 741	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
32	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
33	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 743	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
34	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 747	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
35	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
36	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 749	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
37	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 753	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
38	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
39	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 755	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
40	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 759	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
41	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
42	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 761	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
43	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 765	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
44	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
45	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 767	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
46	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 771	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
47	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
48	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 773	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
49	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 777	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
50	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
51	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 779	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
52	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 783	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
53	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
54	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 785	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
55	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 789	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
56	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
57	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 791	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
58	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 795	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
59	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
60	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 797	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
61	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 801	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
62	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
63	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 803	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
64	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 807	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
65	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
66	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 809	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
67	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 813	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
68	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
69	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 815	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
70	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 819	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
71	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
72	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 821	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
73	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 825	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
74	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
75	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 827	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
76	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 831	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
77	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
78	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 833	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
79	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 837	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
80	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
81	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 839	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
82	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 843	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
83	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
84	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 845	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
85	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 849	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
86	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
87	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 851	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
88	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 855	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
89	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
90	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 857	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
91	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 861	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
92	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
93	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 863	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
94	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 867	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
95	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
96	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 869	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
97	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 873	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
98	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
99	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 875	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
100	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 879	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
101	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
102	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 881	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
103	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 885	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
104	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
105	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 887	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
106	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 891	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
107	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
108	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 893	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
109	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 897	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
110	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
111	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 899	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
112	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 903	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
113	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
114	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 905	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
115	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 909	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
116	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
117	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 911	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex
118	CaM-bind-GEF	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Ras Pathway No. : 915	199.995 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.005(uM)	-	Substrate CaM-Ca4 inact-GEF Product CaM-GEF
	We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995
119	trigger_PKM	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	PKM Pathway No. : 917	9.9998 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate CaM-Ca4 Ca_detector Product Ca.detector_ complex

CaM-Ca4 acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 681	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
2	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
3	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 688	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
4	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
5	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 695	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
6	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
7	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 701	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
8	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
9	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 706	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
10	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
11	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 712	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
12	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
13	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 718	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
14	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
15	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 724	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
16	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
17	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 730	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
18	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
19	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 736	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
20	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
21	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 742	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
22	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
23	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 748	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
24	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
25	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 754	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
26	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
27	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 760	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
28	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
29	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 766	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
30	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
31	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 772	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
32	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
33	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 778	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
34	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
35	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 784	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
36	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
37	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 790	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
38	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
39	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 796	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
40	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
41	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 802	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
42	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
43	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 808	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
44	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
45	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 814	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
46	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
47	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 820	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
48	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
49	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 826	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
50	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
51	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 832	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
52	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
53	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 838	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
54	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
55	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 844	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
56	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
57	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 850	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
58	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
59	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 856	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
60	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
61	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 862	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
62	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
63	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 868	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
64	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
65	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 874	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
66	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
67	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 880	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
68	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
69	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 886	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
70	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
71	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 892	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
72	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
73	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 898	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
74	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
75	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 904	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
76	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
77	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 910	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*
78	diff	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677	0.101 (s^-1)	0.001 (s^-1)	Keq = 0.0099(uM)	9.804sec	Substrate CaM-Ca4 Product CaM-Ca4
79	CaM-Ca3-bind-Ca	Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83	CaM Pathway No. : 916	0.465 (uM^-1 s^-1)	10 (s^-1)	Kd(bf) = 21.5051(uM)	-	Substrate Ca CaM-Ca3 Product CaM-Ca4
	Use K3 = 21.5 uM here from Stemmer and Klee table 3. kb/kf =21.5 6e5 so kf = 7.75e-7, kb = 10*

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