NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for eIF4E_4E-BP_t37_46_s65

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
eIF4E_4E-BP_t37_46_s65 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1101110

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
4EBP89Network
Shared_Object_4EBP mTOR_model 4E-BP_mod 
Rheb-GTP activates mTOR, again with regulation by MAPK, leading to formation of the eIF4F-mRNA complex.

eIF4E_4E-BP_t37_46_s65 acting as a Molecule in  
4EBP Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
eIF4E_4E-BP_t37_46_s654EBP
Accession No. : 89
4E-BP_mod
Pathway No. : 1092
01000No

eIF4E_4E-BP_t37_46_s65 acting as a Summed Molecule in  
4EBP Network
Accession NamePathway NameTargetInput
4EBP
Accession No. : 89
  • Shared_Object_
    4EBP

    Pathway No. : 1090
  • 4E-BP_tot
  • eIF4E-BP_thr37_
    46

  • eIF4E_4E-BP_
    t37_46_s65

  • 4E-BP_thr37_46_
    s65

    4E-BP_t37_46

  • eIF4E_4E-BP_t37_46_s65 acting as a Substrate for an Enzyme in  
    4EBP Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    PP2A  /
    PP2A_4E-BP
    4EBP
    Accession No. : 89
  • Shared_Object_
    4EBP

    Pathway No. : 1090
  • 8.8002814explicit E-S complexSubstrate
  • eIF4E_4E-BP_
    t37_46_s65


    Product
  • eIF4E-BP_thr37_
    46


  • eIF4E_4E-BP_t37_46_s65 acting as a Product of an Enzyme in  
    4EBP Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    MAPK*  /
  • MAPK_4E-BP_
    phospho
  • 4EBP
    Accession No. : 89
  • Shared_Object_
    4EBP

    Pathway No. : 1090
  • 17.90.164explicit E-S complexSubstrate
  • eIF4E-BP_thr37_
    46


    Product
  • eIF4E_4E-BP_
    t37_46_s65


  • eIF4E_4E-BP_t37_46_s65 acting as a Substrate in a reaction in  
    4EBP Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    eIF4E-BP2_disso4EBP
    Accession No. : 89
    4E-BP_mod
    Pathway No. : 1092
    4
    (s^-1)
    1
    (uM^-1 s^-1)
    Kd(cb) = 0.25(uM)-Substrate
  • eIF4E_4E-BP_
    t37_46_s65


    Product
  • 4E-BP_thr37_46_
    s65

    eIF4E



  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.