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Molecule List for Accession AMPAR_CaMKII_weak_coupling (Accession Number65)

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	Name	Pathway Name / Pathway No.	Accession Type	Initial Conc. (uM)	Volume (fL)	Buffered	Sum Total Of
1	CaM-Ca4	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	-
2	PP1-active	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	1.8	0.09	No	-
	Cohen et al Meth Enz 159 390-408 is main source of info conc = 1.8 uM
3	cAMP	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	-
	The conc of this has been a problem. Schaecter and Benowitz use 50 uM, but Shinomura et al have < 5. So I have altered the cAMP-dependent rates in the PKA model to reflect this.
4	Ca	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.08	0.09	No	-
5	CaM-Ca3	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	-
6	CaM-TR2-Ca2	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	-
	This is the intermediate where the TR2 end (the high-affinity end) has bound the Ca but the TR1 end has not.
7	PP2A	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.1111	0.09	No	-
8	CaM-TR2-Ca2-PSD	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.01	No	-
	This is the intermediate where the TR2 end (the high-affinity end) has bound the Ca but the TR1 end has not.
9	CaM-Ca3-PSD	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.01	No	-
10	CaM-Ca4-PSD	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.01	No	-
11	Ca-PSD	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.08	0.01	No	-
12	PKC-active	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.1	0.09	No	-
13	Anchor	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	27.3333	0.01	No	-
14	temp-PIP2	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	2.5	0.09	Yes	-
	This isn't explicitly present in the M&L model, but is obviously needed. I assume its conc is fixed at 1uM for now, which is a bit high. PLA2 is stim 7x by PIP2 @ 0.5 uM (Leslie and Channon BBA 1045:261(1990) Leslie and Channon say PIP2 is present at 0.1 - 0.2mol% range in membs, which comes to 50 nM. Ref is Majerus et al Cell 37 pp 701-703 1984 Lets use a lower level of 30 nM, same ref....
15	PKC-control	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.1	0.09	Yes	-
16	Ca_control_cyt	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.08	0.09	Yes	-
17	Ca_control_PSD	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.08	0.01	Yes	-
18	AMPAR_bulk	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0.0093	5	Yes	-
19	I_845-P	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	A831845_B831* A845_B831 A831845_B A845_B A831_B831845 A_B831845 A831_B845 A_B845*
20	tot_I_GluR12	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. 281	Network	0	0.09	No	I_845 I_845-P I_845_PP

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