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Result: 1 - 11 of 11 rows are displayed

Molecule List for pathway AC (Pathway Number 278) in Accession AMPAR_CaMKII_strong_coupling (Accession Number 64)

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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.

BufferedSum Total Of
1 AC1Network0.07410No
    Starting conc at 20 nM. Reduced conc to 10 nM, 14.8. Arnold 17 Feb 2005. Raised conc back to about 18 nM, for an nInit of precisely 1. 18 Feb. Doubled conc, to compensate for reduced ATP. 18 Feb. Doublec conc again, halved Vmax.
2 AC1-CaMNetwork00No
    This version of cyclase is Calmodulin activated. Gs stims it but betagamma inhibits.
3 AC2Network0.07410No
    Starting at 0.015 uM. 17 Feb 2005: Raised slightly so as to have integer number of molecules. 18 Feb 2005: Doubled, to compensate for reduced ATP.
4 AC2*Network00No
    This version is activated by Gs and by a betagamma and phosphorylation.
5 AMPNetwork00No
6 ATPNetwork20000Yes
    ATP is present in all cells between 2 and 10 mM. See Lehninger
7 CaM.PDE1Network00No
    Activity up 6x following Ca-CaM binding.
8 cAMP-PDENetwork0.55560No
    The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this. 18 Feb 2005: After some playing with initial conc, it is now back at 0.5 uM.
9 cAMP-PDE*Network00No
    This form has about 2X activity as plain PDE. See Sette et al JBC 269:28 18271-18274 1994.
10 cAMP_in_dendNetwork00No
    Assume a 5 uM long segment of 1 uM^2 Xsection dendrite.
11 PDE1Network2.59260No
    CaM-Dependent PDE. Amount calculated from total rate in brain vs. specific rate.

Result: 1 - 11 of 11 rows are displayed

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