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List of mapk occurrences in molecule list for pathway MAPK (Pathway Number 366) in Accession Ajay_Bhalla_2007_Bistable (Accession Number 79)
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|Buffered||Sum Total Of|
|1|| MAPK||Network||3.6||0||No||- |
| || conc is from Sanghera et al JBC 265 pp 52 (1990) A second calculation gives 3.1 uM, from same paper. They est MAPK is 1e-4x total protein, and protein is 15% of cell wt, so MAPK is 1.5e-5g/ml = 0.36uM. which is closer to our first estimate. Lets use this. Updated 16 May 2003. Ortiz et al 1995 J Neurosci 15(2):1285-1297 provide estimates of ERK2 levels in hippocampus: 1009 ng/mg. This comes to about 3.6uM, which may still be an underestimate of synaptic levels. |
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