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Accession Type:
Network
Mammalian_cell_
cycle
Growth
CELLDIV
Rb_grp
IE_GRP
CycB_Grp
 Molecule
 Enzyme
 Reaction
Cdc20_Grp
Cdh1_grp
E2F
CycA_Grp
CycE_grp
Early_Response_
Genes
Delayed_
Response_Genes
CycD_Grp

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Enzyme List for pathway CycB_Grp (Pathway Number 1073)

 Molecule Name/
Site Name
Km (uM) kcat (1/s)Ratio
(k2/k3)
Enzyme TypeSubstrate Product
1 Enzyme Activity:
k1

Enzyme Molecule:
CycB_synth
0.010.64explicit E-S complexCycB_dimer
CycB
  k1 = 0.6. J1 = 0.1 rate = k1([CycB]/J1)^2 / (1 + ([cycB]/J1)^2 ) 2nd order term comes from dimerization, assume rate = k1 * dimer. Doing our usual assumption of AA = Km = 1, we get kcat = 2 * k1 = 1.2 7 April. Revisit this. Multiply expression above and below by J1^2. Then we have standard MM form, with k1 = kcat, and J1^2 = Km. 19 Apr 2005. Altered layout so that dimer form is in substrate, which it should have been all along.


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