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Accession Type:
Network
Mammalian_cell_
cycle
Growth
CELLDIV
 Molecule
 Enzyme
Rb_grp
IE_GRP
CycB_Grp
Cdc20_Grp
Cdh1_grp
E2F
CycA_Grp
CycE_grp
Early_Response_
Genes
Delayed_
Response_Genes
CycD_Grp

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Molecule List for pathway CELLDIV (Pathway Number 1070)

 Name Initial Conc. (uM) Volume (fL) Buffered
1Cdc200200No
2CycA0200No
    rate = k4.Gamma_A * [CycA] * [Cdh1]/(J4 + [Cdh1]) J4 = 0.01 k4 = kcat = 40
3CycB0200No
4CycD0200No
5CycE0200No
6DRG0200No
7E2FA5200No
    This is the active form of E2F. E2FTot = 5, and this is used for the CoInit.
8ERG0200No
    Pool of proteins synthesised by Early Response Genes. Production is inhibited by DRG, the Delayed Response Genes.
9IEP0200No
    Represented as k13.[IEP].[Cdc20A]/(J13 + [Cdc20A]) in other words, a classical MM form. k13 = 5, J13 = 0.005
10Kip10200No
11Mass_dup0200No
12Rb10200No
    Rbtot = 10, assigned to CoInit
13Rb_P0200No
14Tot_Kip10200No

Summed Molecule List

  Target Inputs
1 Mass_dupmass
2 Tot_Kip1CycE_Kip1
Kip1
CycA_Kip1
CycD_Kip1


Pathway Details  Molecule List   Enzyme List  Reaction List  


Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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