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Accession Type:
Network
Mammalian_cell_
cycle
Growth
CELLDIV
Rb_grp
IE_GRP
CycB_Grp
Cdc20_Grp
Cdh1_grp
E2F
CycA_Grp
CycE_grp
Early_Response_
Genes
 Molecule
 Enzyme
 Reaction
Delayed_
Response_Genes
CycD_Grp

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Reaction List for pathway Early_Response_Genes (Pathway Number 1079)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 DRG2_bind_ERG_
synth
kf
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.01(uM)-ERG_synth
DRG_2B
inhib_ERG_synth
  Kd = J15^2 = (0.1)^2 = 0.01
2 k16kf
(s^-1)
0
(s^-1)
--ERG
degraded
  k16 from paper = 0.25, unidirectional degradation step.


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