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Accession Type:
Network
Mammalian_cell_
cycle
Growth
CELLDIV
Rb_grp
IE_GRP
CycB_Grp
Cdc20_Grp
Cdh1_grp
E2F
CycA_Grp
CycE_grp
Early_Response_
Genes
Delayed_
Response_Genes
CycD_Grp
 Molecule
 Reaction

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Reaction List for pathway CycD_Grp (Pathway Number 1081)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 k10kf
(s^-1)
0
(s^-1)
--CycD
degraded
2 k10_bkf
(s^-1)
0
(uM^-1 s^-1)
--CycD_Kip1
degraded
Kip1
  This is another degradation step for CycD, but it happens while the CycD is bound to Kip1. Same rate as k10.
3 k24kf
(uM^-1 s^-1)
10
(s^-1)
Kd(bf) = 0.01(uM)-Kip1
CycD
CycD_Kip1
  k24 = 1000 k24r = 10
4 k_prime6kf
(s^-1)
0
(uM^-1 s^-1)
--CycD_Kip1
degraded
CycD


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