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Accession Type:
Network
Differential syn
thesis of mRNA
Shared Object_
Differential syn
thesis of mRNA
compartment_1compartment_1
 Molecule
 Enzyme
 Reaction
compartment_2compartment_2

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Reaction List for pathway compartment_1 (Pathway Number 1116)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Astar_binds_
CREB		kf
(uM^-1 s^-1)		0.1
(s^-1)		Kd(bf) = 0.1(uM)-A_star
CREB
PP1star_CREB
 
2 Bstar_bind_CREBkf
(uM^-1 s^-1)		0.1
(s^-1)		Kd(bf) = 0.1(uM)-B_star
CREB
MAPKstar_CREB
 
3 CBP_binds_CREB_
CaMKIV		kf
(uM^-1 s^-1)		0.025
(s^-1)		Kd(bf) = 0.2193(uM)-CBP
CaMKIVstar_CREB
  • CBP_pCREB_
    CaMKIV
    •  
    4 CBP_binds_pCREBkf
    (uM^-1 s^-1)    		0.025
    (s^-1)    		Kd(bf) = 0.2193(uM)-CBP
    MAPKstar_CREB
    		CBP_pCREB_CRE
     
    5 CBP_binds_
    PP1CREB    		kf
    (uM^-1 s^-1)    		0.025
    (s^-1)    		Kd(bf) = 0.2193(uM)-CBP
    PP1star_CREB
    		CBP_pCREB_PP1
     
    6 Cstar_bind_CREBkf
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-C_star
    CREB
    		CaMKIVstar_CREB
     
    7 Inact_PP1_nkf
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.2(uM)-PP1_active_n
    I1n
    		PP1_dash_I1n
     
    8 mRNA_degkf
    (s^-1)    		0
    (s^-1)    		--mRNA
    		degraded_mRNA
     
    9 mRNA_degrkf
    (s^-1)    		0
    (s^-1)    		--mRNA_CaMKIV
    		deg_mRNA_CaMKIV
     
    10 mRNA_elonkf
    (s^-1)    		0.0001
    (s^-1)    		Keq = 0.0001(uM)0.694secmRNA_clx_CaMKIV
    		mRNA_CaMKIV
     
    11 mRNA_elongkf
    (s^-1)    		0.0001
    (s^-1)    		Keq = 0.0001(uM)0.694secPP1mRNA_clx
    		PP1_mRNA
     
    12 mRNA_elongationkf
    (s^-1)    		0.0001
    (s^-1)    		Keq = 0.0001(uM)0.694secmRNA_clx
    		mRNA
     
    13 PP1mRNA_degkf
    (s^-1)    		0
    (s^-1)    		--PP1_mRNA
    		deg_PP1mRNA
     
    14 PP1_dissockf
    (s^-1)    		2
    (uM^-1 s^-1)    		Kd(cb) = 2(uM)-PP1_dash_I1n
    		PP1_active_n
    I1n
     
    15 TORC1_bind_CREBkf
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-TORC1n
    CBP_pCREB_CRE
  • Transcription_
    clx
    •  
    16 TORC1_bind_
    CREB_C    		kf
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-TORC1n
  • CBP_pCREB_
    CaMKIV
  • Transcription_
    Clx_C
    •  
    17 TORC1_bind_
    PP1CREB    		kf
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-TORC1n
    CBP_pCREB_PP1
    		Transcr_clx_PP1
     


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    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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