 |  |  Nucleus |
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Reaction List for pathway Shared_Object_RanGTPase (Pathway Number 304) | | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| | Name | Kf | Kb | Kd | tau | Substrate | Product | | 1 |
Cytoplasmic_
transfer | kf
(s^-1) | 1.3
(s^-1) | Not applicable** | - | GTP.Ran-nuclear
| GTP.Ran-cytoplas
mic
| | | Approximation to achieve Cytoplasmic transfer as per kinetics described by Gorlich D et al (2003) EMBO J 22(5):1088-1100 | | 2 |
Nucleoplasmic_
transfer | kf
(s^-1) | 0.1
(s^-1) | Not applicable** | - | NTF2-GDP.Ran
| nuclear-NTF2-GDP
.Ran
| | | Approximation to achieve Nucleoplasmic transfer as per kinetics described by Gorlich D et al (2003) EMBO J 22(5):1088-1100 |
** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration.
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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