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Molecule Parameter List for bisPP-IP3 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics |
bisPP-IP3 participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | No. of occurrences | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | NonOsc_Ca_ IP3metabolism | 23 | Network | MIPP, CaMKII, CaM, PKC, IP3-3K, CaRegulation, Gq, PLCbeta, 134_dephos, 145_dephos, IP4-system, IHP-system, 1345_dephos | This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
bisPP-IP3 acting as a Molecule in NonOsc_Ca_IP3metabolism Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | bisPP-IP3 | NonOsc_Ca_ IP3metabolism Accession No. : 23 | IHP-system Pathway No. : 116 | 0 | 1000 | Yes | Bis(diphospho)inositol trisphosphate from Saiardi et al, JBC 275(32); 2000: 24686-92 |
bisPP-IP3 acting as a Product of an Enzyme in NonOsc_Ca_IP3metabolism Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | IP6_K2 / pp-ip4-k2 | NonOsc_Ca_ IP3metabolism Accession No. : 23 | IHP-system Pathway No. : 116 | 30.0003 | 0.01 | 4 | explicit E-S complex | Substrate PP-IP4
Product bisPP-IP3
| | from Saiardi et al, JBC 275; 2000 approx Km and Vmax calculated from first order rate constants | 2 | IP6-K / pp-ip4-k1 | NonOsc_Ca_ IP3metabolism Accession No. : 23 | IHP-system Pathway No. : 116 | 23.0003 | 0.05 | 4 | explicit E-S complex | Substrate PP-IP4
Product bisPP-IP3
| | from Saiardi et al, JBC 275; 2000 approx Km and Vmax calculated from first order rate constants |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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