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Molecule Parameter List for IP4-3K | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| IP4-3K participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | Osc_Ca_
IP3metabolism | 24 | Network |
MIPP, CaMKII, CaM,
PKC, IP3-3K, Gq,
PLCbeta, 134_dephos, 145_dephos,
IP4-system, IHP-system, 1345_dephos,
CaRegulation, Othmer-Tang-model | | This network models an oscillatory calcium response to GPCR mediated PLCbeta activation, alongwith detailed InsP3 metabolism in the neuron. It differs from the NonOsc_Ca_IP3metabolism network in the CaRegulation module and in InsP3 receptor kinetics. Details of InsP3 receptor kinetics have been adapted from the Othmer-Tang model for oscillatory Ca dynamics. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
IP4-3K acting as a Molecule in Osc_Ca_IP3metabolism Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | IP4-3K | Osc_Ca_
IP3metabolism
Accession No. : 24 | IP4-system
Pathway No. : 129 | 0.0048 | 1000 | No | | Ins(1456)P4 3kinase from Stephens et al, Biochem J 249; 1988: 283-92 |
IP4-3K acting as an Enzyme in Osc_Ca_IP3metabolism Network
Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | IP4-3K /
ip4-3k
| Osc_Ca_
IP3metabolism
Accession No. : 24 | IP4-system
Pathway No. : 129 | 0.399999 | 4.3 | 4 | explicit E-S complex | Substrate
IP4(1456)
Product
IP5(13456)
| | from Stephens et al, Biochem J 249; 1988 |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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