| Name | Osc_Ca_IP3metabolism |
| Accession Type | Network |
| Transcriber | Jyoti Mishra, NCBS |
| Developer | Jyoti Mishra, NCBS |
| Entry Date (YYYY-MM-DD) | 2002-01-08 00:00:00 |
| Species | Generic mammalian |
| Tissue | Brain - Neuronal |
| Cell Compartment | Cytosol |
| Source | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) |
| Methodology | Quantitative match to experiments, Qualitative |
| Model Implementation | Approximate implementation |
| Model Validation | Approximates orginal data |
| Notes | This network models an oscillatory calcium response to GPCR mediated PLCbeta activation, alongwith detailed InsP3 metabolism in the neuron. It differs from the NonOsc_Ca_IP3metabolism network in the CaRegulation module and in InsP3 receptor kinetics. Details of InsP3 receptor kinetics have been adapted from the Othmer-Tang model for oscillatory Ca dynamics. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |
