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Molecule Parameter List for MKK-PP | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| MKK-PP participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 2 | 1 | 1 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| MAPK_osc | 27 | Pathway | MAPK |
| This MAPK model is based on Boris N. Kholodenko Eur J Biochem. (2000) 267(6):1583-8 for data from Xenopus oocytes extracts. | |||
MKK-PP acting as a Molecule in MAPK_osc Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| MKK-PP | MAPK_osc Accession No. : 27 | MAPK Pathway No. : 139 | 0 | 0.0016667 | No | |
| This is the double phosphorylated and active form of MKK from Kholodenko, 2000 | ||||||
MKK-PP acting as an Enzyme in MAPK_osc Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | MKK-PP / 7 | MAPK_osc Accession No. : 27 | MAPK Pathway No. : 139 | 0.0150001 | 0.025 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Substrate MAPK Product MAPK-P |
| The Km is 15nM which is 0.015uM Vmax is 0.025s-1 from Kholodenko, 2000. | ||||||||
| 2 | MKK-PP / 8 | MAPK_osc Accession No. : 27 | MAPK Pathway No. : 139 | 0.0150001 | 0.025 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Substrate MAPK-P Product MAPK-PP |
| The Km is 15nM which is 0.015uM and Vmax is 0.025s-1 from Kholodenko, 2000 | ||||||||
MKK-PP acting as a Substrate for an Enzyme in MAPK_osc Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| int2 / 5 | MAPK_osc Accession No. : 27 | MAPK Pathway No. : 139 | 0.015 | 0.75 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Substrate MKK-PP Product MKK-P |
| The Km is 15nM and Vmax is 0.75nM.s-1 from Kholodenko, 2000 | |||||||
MKK-PP acting as a Product of an Enzyme in MAPK_osc Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| MKKK-P / 4 | MAPK_osc Accession No. : 27 | MAPK Pathway No. : 139 | 0.0150001 | 0.025 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Substrate MKK-P Product MKK-PP |
| Km is 15nM and Vmax is 0.025s-1 from Kholodenko, 2000. | |||||||