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Molecule Parameter List for tot_CaM_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_CaM_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1120000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKII_200349Network
Shared_Object_CaMKII_2003 CaMKII CaM 
PP1 PP2B 
Model of regulation of CaMKII by Calcium, including parallel excitatory input from CaM and inhibitory input from PP1 as regulated by Calcineurin and PKA. Cell type: neuronal.
Bhalla US. Biophys J. 2004 Aug;87(2):733-44.

tot_CaM_CaMKII acting as a Molecule in  
CaMKII_2003 Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
tot_CaM_CaMKIICaMKII_2003
Accession No. : 49
CaMKII
Pathway No. : 202
01000No

tot_CaM_CaMKII acting as a Summed Molecule in  
CaMKII_2003 Network
Accession NamePathway NameTargetInput
CaMKII_2003
Accession No. : 49
CaMKII
Pathway No. : 202
tot_CaM_CaMKIICaMKII-CaM
  • CaMKII-thr286*-C
    aM


  • tot_CaM_CaMKII acting as an Enzyme in  
    CaMKII_2003 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1tot_CaM_CaMKII /
    CaM_act_305
    CaMKII_2003
    Accession No. : 49
    CaMKII
    Pathway No. : 202
    113.664explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
        Rates from autocamtide phosphorylation, from Hanson and Schulman JBC 267:24 17216-17224 1992. Jan 1 1998: Speed up 12x to match fig 5.
    2tot_CaM_CaMKII /
    CaM_act_286
    CaMKII_2003
    Accession No. : 49
    CaMKII
    Pathway No. : 202
    113.6010.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.