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Molecule Parameter List for tot_CaM_CaMKII | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| tot_CaM_CaMKII participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 2 | 2 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | AMPAR_traff_
model0 | 59 | Network |
Shared_Object_AMPAR_traff_model0, CaMKII, CaM,
PP1, PP2B, PP1_PSD,
PKA, AC, AMPAR,
AMPAR_memb | | This is model 0 from Hayer and Bhalla, PLoS Comput Biol 2005. It has a bistable model of AMPAR traffick, plus a
non-bistable model of CaMKII. This differs from the reference model (model 1) in that model0 lacks degradation and turno
ver reactions for AMPAR. |
tot_CaM_CaMKII acting as a Molecule in AMPAR_traff_model0 Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | tot_CaM_CaMKII | AMPAR_traff_
model0
Accession No. : 59 | CaMKII
Pathway No. : 235 | 0 | 0.09 | No | | |
tot_CaM_CaMKII acting as a Summed Molecule in AMPAR_traff_model0 Network
tot_CaM_CaMKII acting as an Enzyme in AMPAR_traff_model0 Network
| | Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | | 1 | tot_CaM_CaMKII /
CaM_act_305
| AMPAR_traff_
model0
Accession No. : 59 | CaMKII
Pathway No. : 235 | 113.601 | 6 | 4 | explicit E-S complex | Substrate
CaMKII-thr286
Product
CaMKII***
| | | Rates from autocamtide phosphorylation, from Hanson and Schulman JBC 267:24 17216-17224 1992. Jan 1 1998: Speed up 12x to match fig 5. | | 2 | tot_CaM_CaMKII /
CaM_act_286
| AMPAR_traff_
model0
Accession No. : 59 | CaMKII
Pathway No. : 235 | 113.602 | 0.5 | 4 | explicit E-S complex | Substrate
CaMKII-CaM
Product
CaMKII-thr286*-C
aM
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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