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Molecule Parameter List for tot_CaM_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_CaM_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1220000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_traff_
    model1
  • 60Network
    Shared_Object_AMPAR_traff_model1 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    PKA AC AMPAR 
    AMPAR_memb 
    This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable.

    tot_CaM_CaMKII acting as a Molecule in  
    AMPAR_traff_model1 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    tot_CaM_CaMKII
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    00.09No

    tot_CaM_CaMKII acting as a Summed Molecule in  
    AMPAR_traff_model1 Network
     Accession NanePathway NameTargetInput
    1
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    tot_CaM_CaMKIICaMKII-CaM
  • CaMKII-thr286*-C
    aM

  • 2
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    act_CaMKII_cyttot_CaM_CaMKII
  • tot_autonomous_
    CaMKII


  • tot_CaM_CaMKII acting as an Enzyme in  
    AMPAR_traff_model1 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1tot_CaM_CaMKII /
    CaM_act_305
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    113.60164explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
        Rates from autocamtide phosphorylation, from Hanson and Schulman JBC 267:24 17216-17224 1992. Jan 1 1998: Speed up 12x to match fig 5.
    2tot_CaM_CaMKII /
    CaM_act_286
  • AMPAR_traff_
    model1

    Accession No. : 60
  • CaMKII
    Pathway No. : 245
    113.6020.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.