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Molecule Parameter List for tot_CaM_CaMKII | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics |
tot_CaM_CaMKII participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | No. of occurrences | 1 | 2 | 2 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | AMPAR_traff_ model1 | 60 | Network | Shared_Object_AMPAR_traff_model1, CaMKII, CaM, PP1, PP2B, PP1_PSD, PKA, AC, AMPAR, AMPAR_memb | This is the basic model of AMPAR trafficking bistability. It is based on Hayer and Bhalla, PLoS Comput. Biol. 2005. It includes the degradation and turnover of AMPARs. The CaMKII portion of the model is not bistable. |
tot_CaM_CaMKII acting as a Molecule in AMPAR_traff_model1 Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | tot_CaM_CaMKII | AMPAR_traff_ model1 Accession No. : 60 | CaMKII Pathway No. : 245 | 0 | 0.09 | No | |
tot_CaM_CaMKII acting as a Summed Molecule in AMPAR_traff_model1 Network
tot_CaM_CaMKII acting as an Enzyme in AMPAR_traff_model1 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | tot_CaM_CaMKII / CaM_act_305
| AMPAR_traff_ model1 Accession No. : 60 | CaMKII Pathway No. : 245 | 113.601 | 6 | 4 | explicit E-S complex | Substrate CaMKII-thr286
Product CaMKII***
| | Rates from autocamtide phosphorylation, from Hanson and Schulman JBC 267:24 17216-17224 1992. Jan 1 1998: Speed up 12x to match fig 5. | 2 | tot_CaM_CaMKII / CaM_act_286
| AMPAR_traff_ model1 Accession No. : 60 | CaMKII Pathway No. : 245 | 113.602 | 0.5 | 4 | explicit E-S complex | Substrate CaMKII-CaM
Product CaMKII-thr286*-C aM
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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