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Molecule Parameter List for tot-auto-PSD | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| tot-auto-PSD participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 2 | 3 | 0 | 0 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
strong_coupling | 64 | Network | Shared_Object_AMPAR_CaMKII_strong_coupling, CaMKII, CaM, PP1, AMPAR_memb, PP2B, PKA, AC, PP1_PSD, AMPAR |
| This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on. | |||
tot-auto-PSD acting as a Molecule in AMPAR_CaMKII_strong_coupling Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| tot-auto-PSD | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | 2 | 0.01 | No | |
tot-auto-PSD acting as a Summed Molecule in AMPAR_CaMKII_strong_coupling Network
| Accession Nane | Pathway Name | Target | Input | |
| 1 | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | tot-auto-PSD | D CaMKII***-PSD PSD |
| 2 | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | actCaMKII-PSD | M-PSD CaMKII-CaM-PSD tot-auto-PSD |
tot-auto-PSD acting as an Enzyme in AMPAR_CaMKII_strong_coupling Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | tot-auto-PSD / auton-305-PSD | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | 500 | 6 | 4 | explicit E-S complex | Substrate D Product CaMKII***-PSD |
| 2 | tot-auto-PSD / auton-286-PSD | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | 500.002 | 0.5 | 4 | explicit E-S complex | Substrate CaMKII-CaM-PSD Product M-PSD |
| 3 | tot-auto-PSD / auton-autoph | strong_coupling Accession No. : 64 | AMPAR_CaMKII_ strong_coupling Pathway No. : 271 | 500.005 | 2 | 4 | explicit E-S complex | Substrate CaMKII-PSD Product D |
color.