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Molecule Parameter List for PKC-Ca-DAG

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PKC-Ca-DAG participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences4000007979

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff2
  • 83NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff PKC MAPK 
    Ras CaM PKM chain kinetics PKC MAPK Ras CaM PKM kinetics[1] 
    PKC MAPK Ras kinetics[3] CaM PKM kinetics[2] PKC MAPK Ras 
    CaM PKM PKC MAPK Ras CaM PKM kinetics[4] PKC MAPK Ras CaM 
    PKM kinetics[5] PKC MAPK Ras CaM PKM kinetics[6] PKC MAPK 
    Ras CaM PKM kinetics[7] PKC MAPK Ras CaM PKM kinetics[8] 
    PKC MAPK Ras CaM PKM kinetics[9] PKC MAPK Ras CaM PKM kinetics[10] 
    PKC MAPK Ras CaM PKM kinetics[11] PKC MAPK Ras CaM PKM kinetics[12] 
    PKC MAPK Ras CaM PKM kinetics[13] PKC MAPK Ras CaM PKM kinetics[14] 
    PKC MAPK Ras CaM PKM kinetics[15] PKC MAPK Ras CaM PKM kinetics[16] 
    PKC MAPK Ras CaM PKM kinetics[17] PKC MAPK Ras CaM PKM kinetics[18] 
    PKC MAPK Ras CaM PKM kinetics[19] PKC MAPK Ras CaM PKM kinetics[20] 
    PKC MAPK Ras CaM PKM kinetics[21] PKC MAPK Ras CaM PKM kinetics[22] 
    PKC MAPK Ras CaM PKM kinetics[23] PKC MAPK Ras CaM PKM kinetics[24] 
    PKC MAPK Ras CaM PKM kinetics[25] PKC MAPK Ras CaM PKM kinetics[26] 
    PKC MAPK Ras CaM PKM kinetics[27] PKC MAPK Ras CaM PKM kinetics[28] 
    PKC MAPK Ras CaM PKM kinetics[29] PKC MAPK Ras CaM PKM kinetics[30] 
    PKC MAPK Ras CaM PKM kinetics[31] PKC MAPK Ras CaM PKM kinetics[32] 
    PKC MAPK Ras CaM PKM kinetics[33] PKC MAPK Ras CaM PKM kinetics[34] 
    PKC MAPK Ras CaM PKM kinetics[35] PKC MAPK Ras CaM PKM kinetics[36] 
    PKC MAPK Ras CaM PKM kinetics[37] PKC MAPK Ras CaM PKM kinetics[38] 
    PKC MAPK Ras CaM PKM 
    This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
    The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.

    PKC-Ca-DAG acting as a Molecule in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 685
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 691
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 698
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 703
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 709
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 715
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 721
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 775
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 727
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 733
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 739
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 745
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 751
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 757
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 763
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 769
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 871
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 781
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 787
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 793
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 799
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 805
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 811
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 817
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 823
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 829
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 835
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 841
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 847
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 853
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 859
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 865
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 877
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 883
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 889
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 895
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 901
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 907
    0.00091.5No
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 678
    0.00091.5Yes
    PKC-Ca-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 913
    0.00091.5Yes

    PKC-Ca-DAG acting as a Substrate in a reaction in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 678
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    2diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    3PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 685
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    5PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 691
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    6diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    7PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 698
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    8diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    9PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 727
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    10PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 703
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    12PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 709
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    14PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 715
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    15diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    16PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 721
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    17diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    18PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 775
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    20diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    21PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 733
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    23PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 739
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    24diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    25PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 745
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    26diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    27PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 751
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    29PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 757
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    30diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    31PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 763
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    32diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    33PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 769
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    35PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 871
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    36diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    37PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 781
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    38diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    39PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 787
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    41PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 793
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    42diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    43PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 799
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    44diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    45PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 805
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    47PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 811
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    48diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    49PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 817
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    50diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    51PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 823
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    52diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    53PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 829
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    54diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    55PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 835
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    56diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    57PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 841
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    58diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    59PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 847
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    60diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    61PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 853
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    62diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    63PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 859
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    64diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    65PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 865
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    66diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    67PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 877
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    68diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    69PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 883
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    70diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    71PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 889
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    72diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    73PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 895
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    74diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    75PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 901
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    76diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    77PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 907
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.
    78diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    79PKC-DAG-to-memb
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 913
    1
    (s^-1)
    0.1
    (s^-1)
    Keq = 0.1(uM)0.909secSubstrate
    PKC-Ca-DAG

    Product
    PKC-DAG-memb*
      Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.

    PKC-Ca-DAG acting as a Product in a reaction in  
    Ajay_Bhalla_2007_ReacDiff2 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 678
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    2diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    3PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 685
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    5PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 703
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    6PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 691
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    8PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 698
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    9diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    10PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 727
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    12PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 709
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    14PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 715
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    15diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    16PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 721
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    17diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    18PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 775
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    20diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    21PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 733
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    23PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 739
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    24diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    25PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 745
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    26diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    27PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 751
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    29PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 757
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    30diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    31PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 763
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    32diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    33PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 769
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    35PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 871
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    36diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    37PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 781
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    38diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    39PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 787
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    41PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 793
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    42diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    43PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 799
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    44diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    45PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 805
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    47PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 811
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    48diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    49PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 817
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    50diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    51PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 823
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    52diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    53PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 829
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    54diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    55PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 835
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    56diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    57PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 841
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    58diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    59PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 847
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    60diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    61PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 853
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    62diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    63PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 859
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    64diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    65PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 865
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    66diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    67PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 877
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    68diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    69PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 883
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    70diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    71PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 889
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    72diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    73PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 895
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    74diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    75PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 901
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    76diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    77PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 907
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
    78diff
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff

    Pathway No. : 677
  • 0.101
    (s^-1)
    0.001
    (s^-1)
    Keq = 0.0099(uM)9.804secSubstrate
    PKC-Ca-DAG

    Product
    PKC-Ca-DAG
    79PKC-act-by-DAG
  • Ajay_Bhalla_
    2007_ReacDiff2

    Accession No. : 83
  • PKC
    Pathway No. : 913
    0.008
    (uM^-1 s^-1)
    8.6348
    (s^-1)
    Kd(bf) = 1079.4148(uM)-Substrate
    DAG
    PKC-Ca

    Product
    PKC-Ca-DAG
      Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8



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