| | Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| 1 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 679 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 2 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 679 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 3 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 686 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 4 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 686 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 5 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 692 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 6 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 692 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 7 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 699 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 8 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 699 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 9 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 704 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 10 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 704 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 11 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 710 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 12 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 710 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 13 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 716 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 14 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 716 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 15 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 722 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 16 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 722 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 17 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 728 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 18 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 728 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 19 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 734 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 20 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 734 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 21 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 740 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 22 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 740 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 23 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 746 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 24 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 746 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 25 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 752 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 26 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 752 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 27 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 758 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 28 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 758 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 29 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 764 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 30 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 764 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 31 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 770 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 32 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 770 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 33 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 776 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 34 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 776 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 35 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 782 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 36 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 782 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 37 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 788 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 38 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 788 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 39 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 794 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 40 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 794 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 41 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 800 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 42 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 800 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 43 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 806 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 44 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 806 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 45 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 812 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 46 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 812 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 47 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 818 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 48 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 818 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 49 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 824 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 50 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 824 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 51 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 830 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 52 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 830 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 53 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 836 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 54 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 836 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 55 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 842 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 56 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 842 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 57 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 848 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 58 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 848 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 59 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 854 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 60 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 854 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 61 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 860 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 62 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 860 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 63 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 866 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 64 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 866 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 65 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 872 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 66 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 872 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 67 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 878 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 68 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 878 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 69 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 884 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 70 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 884 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 71 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 890 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 72 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 890 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 73 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 896 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 74 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 896 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 75 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 902 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 76 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 902 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 77 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 908 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 78 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 908 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 79 | Raf-GTP-Ras / Raf-GTP-Ras.1
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 914 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK
Product MAPKK-ser
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |
| 80 | Raf-GTP-Ras / Raf-GTP-Ras.2
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | MAPK Pathway No. : 914 | 0.159096 | 0.3 | 4 | explicit E-S complex | Substrate MAPKK-ser
Product MAPKK*
|
| | Kinetics are the same as for the craf_1* activity, ie., k1=5.5e-6, k2=0.42, k3 = 0.105 These are basedo n Force et al PNAS USA 91 1270-1274, 1994., but k1 is scaled up 5x (ie., Km is scaled down 5x to the value used here and for craf_1* activity: Km = 0.1591). |