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Molecule Parameter List for CaM-GEF | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_ 2007_ReacDiff2 | 83 | Network | Shared_Object_Ajay_Bhalla_2007_ReacDiff, PKC, MAPK, Ras, CaM, PKM, chain, kinetics, PKC, MAPK, Ras, CaM, PKM, kinetics[1], PKC, MAPK, Ras, kinetics[3], CaM, PKM, kinetics[2], PKC, MAPK, Ras, CaM, PKM, PKC, MAPK, Ras, CaM, PKM, kinetics[4], PKC, MAPK, Ras, CaM, PKM, kinetics[5], PKC, MAPK, Ras, CaM, PKM, kinetics[6], PKC, MAPK, Ras, CaM, PKM, kinetics[7], PKC, MAPK, Ras, CaM, PKM, kinetics[8], PKC, MAPK, Ras, CaM, PKM, kinetics[9], PKC, MAPK, Ras, CaM, PKM, kinetics[10], PKC, MAPK, Ras, CaM, PKM, kinetics[11], PKC, MAPK, Ras, CaM, PKM, kinetics[12], PKC, MAPK, Ras, CaM, PKM, kinetics[13], PKC, MAPK, Ras, CaM, PKM, kinetics[14], PKC, MAPK, Ras, CaM, PKM, kinetics[15], PKC, MAPK, Ras, CaM, PKM, kinetics[16], PKC, MAPK, Ras, CaM, PKM, kinetics[17], PKC, MAPK, Ras, CaM, PKM, kinetics[18], PKC, MAPK, Ras, CaM, PKM, kinetics[19], PKC, MAPK, Ras, CaM, PKM, kinetics[20], PKC, MAPK, Ras, CaM, PKM, kinetics[21], PKC, MAPK, Ras, CaM, PKM, kinetics[22], PKC, MAPK, Ras, CaM, PKM, kinetics[23], PKC, MAPK, Ras, CaM, PKM, kinetics[24], PKC, MAPK, Ras, CaM, PKM, kinetics[25], PKC, MAPK, Ras, CaM, PKM, kinetics[26], PKC, MAPK, Ras, CaM, PKM, kinetics[27], PKC, MAPK, Ras, CaM, PKM, kinetics[28], PKC, MAPK, Ras, CaM, PKM, kinetics[29], PKC, MAPK, Ras, CaM, PKM, kinetics[30], PKC, MAPK, Ras, CaM, PKM, kinetics[31], PKC, MAPK, Ras, CaM, PKM, kinetics[32], PKC, MAPK, Ras, CaM, PKM, kinetics[33], PKC, MAPK, Ras, CaM, PKM, kinetics[34], PKC, MAPK, Ras, CaM, PKM, kinetics[35], PKC, MAPK, Ras, CaM, PKM, kinetics[36], PKC, MAPK, Ras, CaM, PKM, kinetics[37], PKC, MAPK, Ras, CaM, PKM, kinetics[38], PKC, MAPK, Ras, CaM, PKM | This is a 40-compartment reaction-diffusion-transport version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 40 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec In addition, we have a forward (dendrite to soma) transport term of 1 microns/sec. This converts to a rate of 0.1/sec, but applies only to the kf. So the total kf of the diffusion 'reaction' is 0.11 for D = 1 micron^2/sec, and kb is 0.01. If D=0.1 micron^2/sec then kf = 0.101 and kb = 0.001. In addition this model has all molecules buffered in the first and last compartments. This boundary conditions says that the molecules are not drained out of the first compartment, nor do they all pile up in the last one.
The stimulus file pkm_mapk22_transp_endbuf_D1e-13_Fig4CD which was used for the model to replicate Figure 4C and 4D from the paper.
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CaM-GEF acting as a Molecule in Ajay_Bhalla_2007_ReacDiff2 Network
CaM-GEF acting as an Enzyme in Ajay_Bhalla_2007_ReacDiff2 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | 1 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 680 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 2 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 687 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 3 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 693 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 4 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 700 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 5 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 705 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 6 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 711 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 7 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 717 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 8 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 723 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 9 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 729 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 10 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 735 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 11 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 741 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 12 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 747 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 13 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 753 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 14 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 759 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 15 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 765 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 16 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 771 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 17 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 777 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 18 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 783 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 19 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 789 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 20 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 795 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 21 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 801 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 22 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 807 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 23 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 813 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 24 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 819 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 25 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 825 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 26 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 831 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 27 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 837 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 28 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 843 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 29 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 849 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 30 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 855 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 31 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 861 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 32 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 867 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 33 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 873 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 34 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 879 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 35 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 885 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 36 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 891 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 37 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 897 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 38 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 903 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 39 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 909 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. | 40 | CaM-GEF / CaM-GEF-act-ras
| Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 915 | 0.505057 | 0.2 | 4 | explicit E-S complex | Substrate GDP-Ras
Product GTP-Ras
| | Kinetics same as GEF-bg_act-ras, but as of March 17, 2006, the kcat is scaled from 0.02 to 0.2 to have a stronger Ca response for the direct MAPK input. |
CaM-GEF acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
CaM-GEF acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff2 Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | 1 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 680 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 2 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 3 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 687 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 4 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 5 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 693 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 6 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 7 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 700 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 8 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 9 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 705 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 10 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 11 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 711 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 12 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 13 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 717 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 14 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 15 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 723 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 16 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 17 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 729 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 18 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 19 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 735 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 20 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 21 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 741 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 22 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 23 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 747 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 24 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 25 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 753 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 26 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 27 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 759 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 28 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 29 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 765 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 30 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 31 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 771 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 32 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 33 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 777 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 34 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 35 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 783 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 36 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 37 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 789 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 38 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 39 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 795 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 40 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 41 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 801 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 42 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 43 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 807 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 44 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 45 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 813 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 46 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 47 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 819 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 48 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 49 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 825 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 50 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 51 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 831 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 52 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 53 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 837 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 54 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 55 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 843 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 56 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 57 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 849 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 58 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 59 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 855 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 60 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 61 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 861 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 62 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 63 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 867 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 64 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 65 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 873 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 66 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 67 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 879 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 68 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 69 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 885 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 70 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 71 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 891 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 72 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 73 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 897 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 74 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 75 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 903 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 76 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 77 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 909 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 | 78 | diff | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff Pathway No. : 677 | 0.101 (s^-1) | 0.001 (s^-1) | Keq = 0.0099(uM) | 9.804sec | Substrate CaM-GEF
Product CaM-GEF
| 79 | CaM-bind-GEF | Ajay_Bhalla_ 2007_ReacDiff2 Accession No. : 83 | Ras Pathway No. : 915 | 199.995 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.005(uM) | - | Substrate CaM-Ca4 inact-GEF
Product CaM-GEF
| | We have no numbers for this. It is probably between the two extremes represented by the CaMKII phosph states, and I have used guesses based on this. kf=1e-4 kb=1 The reaction is based on Farnsworth et al Nature 376 524-527 1995 |
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