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Molecule Parameter List for ERG_synth | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Mammalian_cell_ cycle | 85 | Network | Growth, CELLDIV, Rb_grp, IE_GRP, CycB_Grp, Cdc20_Grp, Cdh1_grp, E2F, CycA_Grp, CycE_grp, Early_Response_Genes, Delayed_Response_Genes, CycD_Grp | This is a fairly complete mass-action reimplementation of the Novak and Tyson mammalian cell cycle model. It is inexact on two counts. First, it replaces many rather abstracted equations with mass action and Michaelis-Menten forms of enzymes. Second, it does not handle the halving of cellular volume at the division point. Within these limitations, the model does most of what the original paper shows including oscillation of the relevant molecules. |
ERG_synth acting as a Molecule in Mammalian_cell_cycle Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | ERG_synth | Mammalian_cell_ cycle Accession No. : 85 | Early_Response_ Genes Pathway No. : 1079 | 1 | 200 | No | Enzyme that synthesiszes ERG. Enters into equations only implicitly. Initial conc set to 1. |
ERG_synth acting as an Enzyme in Mammalian_cell_cycle Network
Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | ERG_synth / ERG_synth
| Mammalian_cell_ cycle Accession No. : 85 | Early_Response_ Genes Pathway No. : 1079 | 1.00002 | 0.5 | 4 | explicit E-S complex | Substrate AminoAcids
Product ERG
| kcat = 2 * k15 = 0.5 Km = 1 [AA] = 1 |
ERG_synth acting as a Substrate in a reaction in Mammalian_cell_cycle Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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