Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for CycB_synth

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CycB_synth participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Mammalian_cell_
    cycle
    		• 85Network
    Growth,  CELLDIV,  Rb_grp,  
    IE_GRP,  CycB_Grp,  Cdc20_Grp,  
    Cdh1_grp,  E2F,  CycA_Grp,  
    CycE_grp,  Early_Response_Genes,  Delayed_Response_Genes,  
    CycD_Grp 
    This is a fairly complete mass-action reimplementation of the Novak and Tyson mammalian cell cycle model. It is inexact on two counts. First, it replaces many rather abstracted equations with mass action and Michaelis-Menten forms of enzymes. Second, it does not handle the halving of cellular volume at the division point. Within these limitations, the model does most of what the original paper shows including oscillation of the relevant molecules.

    CycB_synth acting as a Molecule in      Mammalian_cell_cycle Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    CycB_synth
  • Mammalian_cell_
    cycle
    Accession No. : 85
    		• CycB_Grp
    Pathway No. : 1073    		1200Yes

    CycB_synth acting as an Enzyme in      Mammalian_cell_cycle Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    CycB_synth /
    k1
  • Mammalian_cell_
    cycle
    Accession No. : 85
    		• CycB_Grp
    Pathway No. : 1073    		0.010.64explicit E-S complexSubstrate
    CycB_dimer

    Product
    CycB
    k1 = 0.6. J1 = 0.1 rate = k1([CycB]/J1)^2 / (1 + ([cycB]/J1)^2 ) 2nd order term comes from dimerization, assume rate = k1 * dimer. Doing our usual assumption of AA = Km = 1, we get kcat = 2 * k1 = 1.2 7 April. Revisit this. Multiply expression above and below by J1^2. Then we have standard MM form, with k1 = kcat, and J1^2 = Km. 19 Apr 2005. Altered layout so that dimer form is in substrate, which it should have been all along.