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Molecule Parameter List for Ras-GTP_PI3K

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Ras-GTP_PI3K participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
BDNF_Receptor86Network
Shared_Object_BDNF_Receptor TrKB_mod PI3K_mod 
BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3.

Ras-GTP_PI3K acting as a Molecule in  
BDNF_Receptor Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Ras-GTP_PI3KBDNF_Receptor
Accession No. : 86
  • Shared_Object_
    BDNF_Receptor

    Pathway No. : 1082
  • 0999.97No

    Ras-GTP_PI3K acting as an Enzyme in  
    BDNF_Receptor Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    Ras-GTP_PI3K /
  • PIP2_phospho_
    Ras-GTP
  • BDNF_Receptor
    Accession No. : 86
  • Shared_Object_
    BDNF_Receptor

    Pathway No. : 1082
  • 4.0000244explicit E-S complexSubstrate
    PIP2

    Product
    PIP3

    Ras-GTP_PI3K acting as a Product in a reaction in  
    BDNF_Receptor Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • PI3K_bind_
    Ras-GTP
  • BDNF_Receptor
    Accession No. : 86
  • Shared_Object_
    BDNF_Receptor

    Pathway No. : 1082
  • 0
    (s^-1)
    5
    (s^-1)
    Keq = 1666666.6667(uM)-Substrate
    PI3K

    Product
    Ras-GTP_PI3K



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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