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Molecule Parameter List for PIP3_PDK2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PIP3_PDK2 participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| AKT | 87 | Network | Shared_Object_AKT, AKT_mod |
| This is one of the sub-model of BDNF signaling cascade. PIP3 activies AKT, leading to accumulation of Rheb-GTP, a regulator of mTOR. | |||
PIP3_PDK2 acting as a Molecule in AKT Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered |
| PIP3_PDK2 | AKT Accession No. : 87 | AKT_mod Pathway No. : 1086 | 0.003 | 999.97 | No |
PIP3_PDK2 acting as an Enzyme in AKT Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| PIP3_PDK2 / phosp_AKTser473 | AKT Accession No. : 87 | AKT_mod Pathway No. : 1086 | 0.800013 | 20 | 4 | explicit E-S complex | Substrate PIP3_AKT_thr308 Product s473 |