 |  |  Delayed_
Response_Genes |
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Enzyme List for pathway Growth (Pathway Number 1069) | | Molecule Name/
Site Name | Km (uM) | kcat (1/s) | Ratio
(k2/k3) | Enzyme Type | Substrate | Product |
| 1 |
Enzyme Activity:
k27
Enzyme Molecule:
mass | 10 | 2 | 4 | explicit E-S complex | Heaviside_dup
| GM
| | | Equation 17 dGM/dt = k27 * mass * Heaviside_out. k27 = 0.2 If k3 << k2, we have ES ~ E.S.k1/k2 and rate = k3 * ES. So we assume k2 = 1, k3 = 0.1, then k1 = 10 * k27 so k1 = 2. This gives a rather low Km, leading to much complex formation. Let us use MM form, and assume Km >> Heaviside_out. Take Km = 10, then kcat = Km * k27 = 2 |
| 2 |
Enzyme Activity:
mu
Enzyme Molecule:
GM | 1.00001 | 0.122 | 4 | explicit E-S complex | AminoAcids
| mass
| | | Rate = E.S.kcat/(Km + S) We want to represent dmass/dt = epsilon.mu.GM. Epsilon is 1 for now. mu = 0.061 S here is AA, buffered to 1. We assign Km = 1 for simplicity. Then kcat = 2 * mu = 0.122 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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