 |  |  CaRegulation |
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Enzyme List for pathway Othmer-Tang-model (Pathway Number 133) | | Molecule Name/
Site Name | Km (uM) | kcat (1/s) | Ratio
(k2/k3) | Enzyme Type | Substrate | Product |
| 1 |
Enzyme Activity:
ER_pump
Enzyme Molecule:
ER_pump | 0.150007 | 10 | 4 | explicit E-S complex | Ca
| Ca-sequester
| | | Othmer and Tang use a Km of 0.5 uM, but this does not generate proper Ca oscillations in our model. So we have decreased Km to 0.15 uM. This is closer to the 0.1 uM value used by Keizer and De Young in Tang et al, Biophys J 70, 1996 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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