 |  |  AC |
Enter a Search String | | Special character and space not allowed in the query term.
Search string should be at least 2 characters long. |
Molecule List for pathway PKA (Pathway Number 135) | | Name | Initial Conc. (uM) | Volume (fL) | Buffered | | 1 | cAMP.R2C2 | 0 | 1000 | No | | | CoInit was .0624 | | 2 | cAMP2.R2C2 | 0 | 1000 | No | | | | | 3 | cAMP3.R2C2 | 0 | 1000 | No | | | | | 4 | cAMP4.R2 | 0 | 1000 | No | | | Starts at 0.15 for the test of fig 6 in Smith et al, but we aren't using that paper any more. | | 5 | cAMP4.R2C | 0 | 1000 | No | | | | | 6 | cAMP4.R2C2 | 0 | 1000 | No | | | | | 7 | inhibited-PKA | 0 | 1000 | No | | | | | 8 | PKA-inhibitor | 0.25 | 1000 | No | | | About 25% of PKA C subunit is dissociated in resting cells without having any noticable activity. Doskeland and Ogreid Int J biochem 13 pp1-19 suggest that this is because there is a corresponding amount of inhibitor protein. | | 9 | R2C2 | 0.5 | 1000 | No | | | This is the R2C2 complex, consisting of 2 catalytic (C) subunits, and the R-dimer. See Taylor et al Ann Rev Biochem 1990 59:971-1005 for a review. The Doskeland and Ogreid review is better for numbers. Amount of PKA is about .5 uM. |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
|
