 |  |  MKP3 |
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Molecule List for pathway PLCbeta (Pathway Number 332) | | Name | Initial Conc. (uM) | Volume (fL) | Buffered | | 1 | Inositol | 0 | 1.5 | Yes | | 2 | PC | 0 | 2.5E-6 | Yes | | | Phosphatidylcholine is the main (around 55%) metabolic product of DAG, follwed by PE (around 25%). Ref is Welsh and Cabot, JCB35:231-245(1987) | | 3 | PLC | 0.8 | 1.5 | No | | | Total PLC = 0.8 uM see Ryu et al JBC 262 (26) pp 12511 1987 | | 4 | PLC-Ca | 0 | 1.5 | No | | 5 | PLC-Ca-Gq | 0 | 1.5 | No | | | This should really be labelled PLC-G*GTP-Ca. This is the activated form of the enzyme. Mahama and Linderman assume that the IP3 precursors are not rate-limiting, but I will include those for completeness as they may be needed later. | | 6 | PLC-Gq | 0 | 1.5 | No |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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