Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Reaction List for pathway EGFR (Pathway Number 223)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 r13
(uM^-1 s^-1)		0.06
(s^-1)		Kd(bf) = 0.02(uM)-EGF
R
Ra
  Taken from Kholodenko et al 1999.
2 r100.01
(uM^-1 s^-1)		0.06
(s^-1)		Kd(bf) = 6(uM)-R-G
SOS
R-G-S
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
3 r110.03
(s^-1)		4.5
(uM^-1 s^-1)		Kd(cb) = 150(uM)-R-G-S
G-S
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
4 r120.0015
(s^-1)		0.1
(uM^-1 s^-1)		Kd(cb) = 66.6667(uM)-G-S
Grb
SOS
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
5 r1390
(uM^-1 s^-1)		0.6
(s^-1)		Kd(bf) = 0.0067(uM)-RP
Shc
R-Sh
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
6 r146
(s^-1)		0.06
(s^-1)		Keq = 0.01(uM)0.165secR-Sh
R-ShP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
7 r150.3
(s^-1)		0.9
(uM^-1 s^-1)		Kd(cb) = 3(uM)-R-ShP
ShP
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
8 r173
(uM^-1 s^-1)		0.1
(s^-1)		Kd(bf) = 0.0333(uM)-R-ShP
Grb
R-Sh-G
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
9 r180.3
(s^-1)		0.9
(uM^-1 s^-1)		Kd(cb) = 3(uM)-R-Sh-G
Sh-G
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
10 r1910
(uM^-1 s^-1)		0.0214
(s^-1)		Kd(bf) = 0.0021(uM)-R-Sh-G
SOS
R-Sh-G-S
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
11 r210
(uM^-1 s^-1)		0.1
(s^-1)		Keq = 0.01(uM)-Ra
Ra
R2
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
12 r200.12
(s^-1)		0.24
(uM^-1 s^-1)		Kd(cb) = 2(uM)-R-Sh-G-S
Sh-G-S
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
13 r213
(uM^-1 s^-1)		0.1
(s^-1)		Kd(bf) = 0.0333(uM)-ShP
Grb
Sh-G
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
14 r2230
(uM^-1 s^-1)		0.064
(s^-1)		Kd(bf) = 0.0021(uM)-Sh-G
SOS
Sh-G-S
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
15 r230.1
(s^-1)		21
(uM^-1 s^-1)		Kd(cb) = 210(uM)-Sh-G-S
G-S
ShP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
16 r249
(uM^-1 s^-1)		0.0429
(s^-1)		Kd(bf) = 0.0048(uM)-R-ShP
G-S
R-Sh-G-S
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
17 r251
(s^-1)		0.03
(s^-1)		Keq = 0.03(uM)0.971secPLCrP
PLCr-I
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
18 r31
(s^-1)		0.01
(s^-1)		Keq = 0.01(uM)0.99secR2
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
19 r560
(uM^-1 s^-1)		0.2
(s^-1)		Kd(bf) = 0.0033(uM)-RP
PLCr
R-PL
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
20 r61
(s^-1)		0.05
(s^-1)		Keq = 0.05(uM)0.952secR-PL
R-PLP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
21 r70.3
(s^-1)		6
(uM^-1 s^-1)		Kd(cb) = 20(uM)-R-PLP
PLCrP
RP
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
22 r93
(uM^-1 s^-1)		0.05
(s^-1)		Kd(bf) = 0.0167(uM)-RP
Grb
R-G
  Taken from Kholodenko BN et al J Biol Chem. (1999) 274(42):30169-81.
Pathway DetailMolecule ListEnzyme ListReaction List