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Accession Type:
Network
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Shared_Object_
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PKC
PLA2
PLCbeta
Gq
MAPK
Ras
 Molecule
 Enzyme
 Reaction
CaMKII
CaM
PP1
PP2B
PKA
AC

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Reaction List for pathway Ras (Pathway Number 25)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 bg-act-GEF6
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.1667(uM)-BetaGamma
inact-GEF
GEF-Gprot-bg
2 CaM-bind-GEF60
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 0.0167(uM)-inact-GEF
CaM-Ca4
CaM-GEF
3 dephosph-GAP0.1
(s^-1)
0
(s^-1)
--GAP*
GAP
4 dephosph-GEF1
(s^-1)
0
(s^-1)
--GEF*
inact-GEF
5 dephosph-inact-G
EF*
1
(s^-1)
0
(s^-1)
--inact-GEF*
inact-GEF
6 Ras-intrinsic-GT
Pase
0.0001
(s^-1)
0
(s^-1)
--GTP-Ras
GDP-Ras


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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