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Reaction List for pathway L-Arginine (Pathway Number 308)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Arginine_
binding		250
(uM^-1 s^-1)		125000
(s^-1)		Kd(bf) = 500(uM)-L-Arginine
Im-nNOS
  • Im-nNOS-L-Argini
    ne
    •   Binding of L-Arginine to Imidazole bound rat brain neuronal Nitric Oxide Synthase. Kd = 0.5mM = 500uM. Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51.
    2 Imidazole_
    release    		81
    (s^-1)    		0.45
    (uM^-1 s^-1)    		Kd(cb) = 0.0056(uM)-
  • Im-nNOS-L-Argini
    ne
    		• nNOS-L-Arginine
    Imidazole
      Release of Imidazole from complex of L-Arginine and Imidazole bound rat brain neuronal Nitric Oxide Synthase. Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51.
    Pathway DetailMolecule ListEnzyme ListReaction List