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Reaction List for pathway L-Arginine (Pathway Number 308) | | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| | Name | Kf | Kb | Kd | tau | Substrate | Product | | 1 |
Arginine_
binding | kf
(uM^-1 s^-1) | 125000
(s^-1) | Kd(bf) = 500(uM) | - | L-Arginine
Im-nNOS
| Im-nNOS-L-Argini
ne
| | | Binding of L-Arginine to Imidazole bound rat brain neuronal Nitric Oxide Synthase. Kd = 0.5mM = 500uM. Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. | | 2 |
Imidazole_
release | kf
(s^-1) | 0.45
(uM^-1 s^-1) | Kd(cb) = 0.0056(uM) | - | Im-nNOS-L-Argini
ne
| nNOS-L-Arginine
Imidazole
| | | Release of Imidazole from complex of L-Arginine and Imidazole bound rat brain neuronal Nitric Oxide Synthase. Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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