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Parameters for Gq (Pathway Number 111) Pathway Layout
Pathway Basic Parameters | Pathway Name | Gq | | Pathway Entry Number | 111 | | Accession Number | 23 | | Accession Name | NonOsc_Ca_IP3metabolism | | Species | Generic mammalian | | Tissue | Brain - Neuronal | | CellCompartment | Cytosol | | Related Pathways | 5,
23,
74,
125,
150,
163,
210,
316,
334,
351
| | Notes | The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein G et al J Biol Chem. 1992 Apr 25;267(12):8081-8. Structure of receptor activation of Gq from Fay SP et al Biochemistry. 1991 May 21;30(20):5066-75.This mGluR/Gq model lacks a mechanism for receptor desensitization.
| Statistics Conversion formatThis pathway is part of accession 23 and is completely specified in the file acc23.g.
There is no separate files for just this pathway. |
| Format | File | | Native Format (GENESIS format) | acc23.g | | GENESIS Format (Annotated version) | Anno_acc23.g |
Pathway Detail Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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