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Molecule List for pathway PLCbeta (Pathway Number 73) in Accession Synaptic_Network (Accession Number 16) | Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering. arrow indicates that ordering is done according to ascending or descending order. The entries are grouped according to Pathway Number and are alternately color coded using and color. |
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Name | Accession Type | Initial Conc. (uM) | Volume (fL) | Buffered | Sum Total Of | 1 | Inositol | Network | 0 | 0 | Yes | - | | Very simplified degradation product of IP3. There is a very interesting and complex phosphorylation/dephosphorylation cascade on the inositol phosphates, but that is outside the scope of this model. | 2 | PC | Network | 0 | 0 | Yes | - | | Phosphatidylcholine is the main (around 55%) metabolic product of DAG, follwed by PE (around 25%). Ref is Welsh and Cabot, JCB35:231-245(1987) | 3 | PLC | Network | 0.8 | 0 | No | - | | Total PLC = 0.8 uM see Ryu et al JBC 262 (26) pp 12511 1987 | 4 | PLC-Ca | Network | 0 | 0 | No | - | | Ca-bound form of PLCbeta. This form is moderately active. Reviewed in Sternweis et al 1992 Phil Trans Roy Soc. Lond. | 5 | PLC-Ca-Gq | Network | 0 | 0 | No | - | | This should really be labelled Ca.GTP.Gq_alpha.PLC This is the activated form of the enzyme. | 6 | PLC-Gq | Network | 0 | 0 | No | - | | Gq-bound form of PLC beta. |
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