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Accession Type:
Network
Ajay_Bhalla_
2007_ReacDiff1_
1e-13
Shared_Object_
Ajay_Bhalla_
2007_ReacDiff1_
1e-13
PKC
MAPK
Ras
CaM
PKM
chain
Shared Object_
Ajay_Bhalla_
2007_ReacDiff1_
1e-13
PKC
MAPK
Ras
CaM
PKM
kinetics[1]
PKC
MAPK
Ras
CaM
PKM
kinetics[2]
PKC
MAPK
Ras
CaM
PKM
kinetics[3]
PKC
MAPK
Ras
CaM
PKM
kinetics[4]
PKC
MAPK
Ras
CaM
PKM
kinetics[5]
PKC
MAPK
Ras
kinetics[6]
CaM
PKM
PKC
MAPK
Ras
CaM
PKM
kinetics[7]
PKC
MAPK
Ras
CaM
PKM
kinetics[8]
PKC
MAPK
Ras
CaM
PKM
kinetics[9]
PKC
MAPK
Ras
CaM
PKM
kinetics[10]
PKC
MAPK
Ras
CaM
PKM
kinetics[11]
PKC
MAPK
Ras
CaM
PKM
kinetics[12]
PKC
MAPK
Ras
CaM
PKM
kinetics[13]
PKC
MAPK
Ras
CaM
PKM
kinetics[14]
PKC
MAPK
Ras
CaM
PKM
kinetics[15]
PKC
MAPK
Ras
CaM
PKM
kinetics[16]
PKC
MAPK
Ras
CaM
PKM
kinetics[17]
PKC
MAPK
Ras
CaM
PKM
kinetics[18]
PKC
MAPK
Ras
CaM
PKM
kinetics[19]
PKC
MAPK
Ras
CaM
PKM
kinetics[20]
PKC
MAPK
Ras
CaM
PKM
kinetics[21]
PKC
MAPK
Ras
CaM
PKM
kinetics[22]
PKC
MAPK
Ras
CaM
PKM
kinetics[23]
PKC
MAPK
Ras
CaM
PKM

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Accession information for Ajay_Bhalla_2007_ReacDiff1_1e-13 (Accession Number 82)

Reaction Scheme

Accession Basic Parameters

Name Ajay_Bhalla_2007_ReacDiff1_1e-13
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2006-12-08
Species Rat
Tissue Hippocampal CA1
Cell Compartment Dendrite
Source Ajay_Bhalla_bistable_model. HFSP Journal. 2007 May;1(1):1-87
Methodology Semi-Quantitative match to experiments
Model Implementation Exact GENESIS implementation
Model Validation Replicates original data
Notes This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_PKM model. The original single-compartment model is repeated 25 times. In addition, a subset (27 out of 42) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. For D = 1e-12 m^2/sec (i.e., 1 micron^2/sec ) the kf and kb of this reaction for these 10 micron compartments are both 0.01/sec. For D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) the kf and kb are 0.001/sec.
The stimulus file pkm_mapk22_diff_1e-13_Fig4B which was used for the model to replicate Figure 4B from the paper.
pkm_mapk22_diff_1e-13_Fig4H replicate Figure 4H.
pkm_mapk22_diff_1e-13_Fig4I replicate Figure 4I.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc82.g   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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